Description:

Transcription factors (TFs) are a group of cellular proteins that play essential roles in regulating gene expression. They act as sensors to monitor cellular change and convert the signals into altered gene expression. Often, a specific cellular signal pathway can activate multiple TFs and the expression of a specific gene is under control of multiple TFs. Hence, monitoring the activation of multiple TFs simultaneously is critical to understand the molecular mechanism of cellular regulation underlying cell signaling and gene expression. Signosis’ TF activation profiling plate array III FA-1011 is used for monitoring 48 different TFs including ATF6, CHOP, Nanog , and SREBP1.

Applicable Grid:

List of Applicable TFs:

123

4

5

6

78910

11

12AAHREvl-1INSM2MNF1PITX2SREBP1AHREvl-1INSM1MNF1PITX2SREBP1BATF3FXRISGFMTFPRDM14TBETATF3FXRISGFMTFPRDM14TBETCATF6GBX2KRF1NanogPROP1TBX3ATF6GBX2KRF1NanogPROP1TBX3DCHOPGKLFLRH-1Nhlh1(HEN)pu.1TeadCHOPGKLFLRH-1Nhlh1(HEN)pu.1TeadEE12/E47HES1LXRNotchRESTTFEBE12/E47HES1LXRNotchRESTTFEBFEBF1HFH1MAFNUR77RREBTGIF/Meis2EBF1HFH1MAFNUR77RREBTGIF/Meis2GEBP-80HLFMIBPOLIG1SIXTwist1EBP-80HLFMIBPOLIG1SIXTwist1HEKLFHOXA4MITFPEA3/EVT4Sperm1VAX2EKLFHOXA4MITFPEA3/EVT4Sperm1VAX2